Nakanishi S, Yamane K, Kamei N, Okubo M, Kohno N
Department of Molecular and Internal Medicine, Division of Clinical Medical Science, Programs for Applied Biomedicine, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan.
Aging Male. 2004 Jun;7(2):113-9. doi: 10.1080/13685530412331284713.
Erectile dysfunction frequently occurs with diabetes mellitus. A survey of diabetic men was conducted by anonymous questionnaire to investigate the associations of erectile dysfunction with various predictive factors. A total of 112 diabetic males without an obvious history of erectile dysfunction were available for analyses. The mean age and duration of diabetes were 53.7 +/- 12.2 years and 10.2 +/- 8.6 years (mean +/- standard deviation), respectively. The questionnaire included questions on the presence or absence of smoking, hypertension, libido and subjective symptoms of diabetic neuropathy that may be associated with erectile dysfunction. Analysis of the answers to the questionnaire revealed that 40% of the patients complained of erectile dysfunction (erection 'always insufficient'). Erectile dysfunction was significantly correlated with age (p = 0.005), but not with duration of diabetes (p = 0.25), adjusted for age. Erectile dysfunction was also associated with sensory neuropathy and reduced libido, independently of age. The logistic regression analysis revealed that erectile dysfunction was positively associated with reduced libido and age. The odds ratio of erectile dysfunction for reduced compared to unreduced libido was 18.21, suggesting that psychogenic factors have a marked influence on erectile dysfunction. It is concluded that the presence of erectile dysfunction should be considered when symptoms related to diabetic neuropathy are observed; psychological approaches, such as sexual counseling, could be applied for the treatment of erectile dysfunction.
勃起功能障碍常与糖尿病并发。通过匿名问卷调查对糖尿病男性进行了一项调查,以研究勃起功能障碍与各种预测因素之间的关联。共有112名无明显勃起功能障碍病史的糖尿病男性可供分析。糖尿病患者的平均年龄和病程分别为53.7±12.2岁和10.2±8.6岁(平均值±标准差)。问卷包括关于吸烟、高血压、性欲以及可能与勃起功能障碍相关的糖尿病神经病变主观症状是否存在的问题。对问卷答案的分析显示,40%的患者抱怨有勃起功能障碍(勃起“总是不充分”)。在对年龄进行校正后,勃起功能障碍与年龄显著相关(p = 0.005),但与糖尿病病程无关(p = 0.25)。勃起功能障碍还与感觉神经病变和性欲减退相关,且与年龄无关。逻辑回归分析显示,勃起功能障碍与性欲减退和年龄呈正相关。性欲减退与未减退相比,勃起功能障碍的优势比为18.21,这表明心理因素对勃起功能障碍有显著影响。结论是,当观察到与糖尿病神经病变相关的症状时,应考虑勃起功能障碍的存在;心理治疗方法,如性咨询,可用于治疗勃起功能障碍。