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蓄意自伤后的自杀:一项为期4年的队列研究。

Suicide after deliberate self-harm: a 4-year cohort study.

作者信息

Cooper Jayne, Kapur Navneet, Webb Roger, Lawlor Martin, Guthrie Else, Mackway-Jones Kevin, Appleby Louis

机构信息

Centre for Suicide Prevention, University of Manchester, 7th Floor, Williamson Building, Oxford Road, Manchester M13 9PL, UK.

出版信息

Am J Psychiatry. 2005 Feb;162(2):297-303. doi: 10.1176/appi.ajp.162.2.297.

Abstract

OBJECTIVE

The purposes of this study were to estimate suicide rates up to 4 years after a deliberate self-harm episode, to investigate time-period effects on the suicide rate over the follow-up period, and to examine potential sociodemographic and clinical predictors of suicide within this cohort.

METHOD

This prospective cohort study included 7,968 deliberate self-harm attendees at the emergency departments of four hospital trusts in the neighboring cities of Manchester and Salford, in northwest England, between September 1, 1997, and August 31, 2001. Suicide rates and standardized mortality ratios (SMRs) for the cohort were calculated. Potential risk factors were investigated by using Cox's proportional hazards models.

RESULTS

Sixty suicides occurred in the cohort during the follow-up period. An approximately 30-fold increase in risk of suicide, compared with the general population, was observed for the whole cohort. The SMR was substantially higher for female patients than for male patients. Suicide rates were highest within the first 6 months after the index self-harm episode. The independent predictors of subsequent suicide were avoiding discovery at the time of self-harm, not living with a close relative, previous psychiatric treatment, self-mutilation, alcohol misuse, and physical health problems.

CONCLUSIONS

The results highlight the importance in a suicide prevention strategy of early intervention after an episode of self-harm. Treatment should include attention to physical illness, alcohol problems, and living circumstances. Self-harm appears to confer a particularly high risk of suicide in female patients.

摘要

目的

本研究旨在估算蓄意自伤事件发生后长达4年的自杀率,调查随访期间自杀率的时间效应,并检验该队列中自杀的潜在社会人口学和临床预测因素。

方法

这项前瞻性队列研究纳入了1997年9月1日至2001年8月31日期间,在英格兰西北部曼彻斯特和索尔福德相邻城市的四家医院信托机构急诊科就诊的7968名蓄意自伤患者。计算该队列的自杀率和标准化死亡比(SMR)。使用Cox比例风险模型调查潜在风险因素。

结果

随访期间该队列中有60例自杀事件发生。整个队列的自杀风险与普通人群相比增加了约30倍。女性患者的SMR显著高于男性患者。自杀率在首次自伤事件后的前6个月内最高。后续自杀的独立预测因素包括自伤时避免被发现、未与近亲同住、既往接受过精神科治疗、自残、酗酒以及身体健康问题。

结论

研究结果突出了自伤事件后早期干预在自杀预防策略中的重要性。治疗应包括关注身体疾病、酒精问题和生活环境。自伤似乎使女性患者面临特别高的自杀风险。

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