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自膨式金属支架缓解胃出口梗阻和近端小肠梗阻:单中心系列研究

Palliation of gastric outlet obstruction and proximal small bowel obstruction with self-expandable metal stents: a single center series.

作者信息

Mosler Patrick, Mergener Klaus D, Brandabur John J, Schembre Drew B, Kozarek Richard A

机构信息

Virginia Mason Medical Center, Section of Gastroenterology, Seattle, WA 98101, USA.

出版信息

J Clin Gastroenterol. 2005 Feb;39(2):124-8.

Abstract

BACKGROUND

Self-expandable metal stents (SEMS) are being increasingly used to palliate malignant stenoses of the gastric outlet and proximal small bowel. Accordingly, we reviewed our experience in this setting.

METHODS

Patients with gastric outlet or proximal small bowel stents were identified by reviewing hospital charts. Outcome criteria included survival data, need for reintervention, and clinical improvement.

RESULTS

A total of 52 SEMS were placed in 36 patients with nonesophageal upper GI stenosis. Initial stent placement was successful in 92% and clinical improvement documented in 75%. Mean survival of patients who eventually died was 3.5 months. Seven patients are alive (mean follow-up, 5.0 months). Stent dysfunction occurred in 36% and required subsequent interventions. Biliary obstruction was documented in 50% of patients, 12 of whom had previously undergone biliary stenting and 5 who needed subsequent biliary decompression.

CONCLUSIONS

Enteral stent placement has been reported to be an effective alternative for palliation of high-risk surgical patients with malignant gastric outlet and small bowel obstruction. Considering the short life expectancy of these patients and significant complications including stent migration, perforation, biliary obstruction, and need for subsequent endoscopic, radiologic and surgical interventions, the authors suggest that this procedure be performed in experienced centers on selected patients only and that biliary decompression be ensured early.

摘要

背景

自膨式金属支架(SEMS)越来越多地用于缓解胃出口和近端小肠的恶性狭窄。因此,我们回顾了我们在这种情况下的经验。

方法

通过查阅医院病历确定胃出口或近端小肠支架置入患者。结果标准包括生存数据、再次干预的必要性和临床改善情况。

结果

36例非食管上消化道狭窄患者共置入52枚SEMS。初次支架置入成功率为92%,75%有临床改善记录。最终死亡患者的平均生存期为3.5个月。7例患者存活(平均随访5.0个月)。支架功能障碍发生率为36%,需要后续干预。50%的患者有胆道梗阻,其中12例先前已行胆道支架置入,5例需要后续胆道减压。

结论

肠内支架置入术已被报道为高危手术患者恶性胃出口和小肠梗阻姑息治疗的有效替代方法。考虑到这些患者预期寿命短以及包括支架移位、穿孔、胆道梗阻以及需要后续内镜、放射和手术干预等严重并发症,作者建议该手术仅在有经验的中心对选定患者进行,并应尽早确保胆道减压。

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