葡萄膜黑色素瘤转移的筛查。文献综述。

Screening for uveal melanoma metastasis. Literature review.

作者信息

Missotten G S, Keunen J E E

机构信息

Department of Ophthalmology, Leiden University Medical Center, Leiden University, The Netherlands.

出版信息

Bull Soc Belge Ophtalmol. 2004(294):13-22.

DOI:

PMID:15682915

Abstract

Local tumour control in uveal melanoma has improved in the last decades. However, 5-year mortality due to metastases from large uveal melanomas remains high. Recently both isolated liver perfusion therapy and chemotherapy have reached encouraging results in improving metastasis survival. As such screening at an early stage, especially for liver metastases, becomes imperative.

摘要

在过去几十年中，葡萄膜黑色素瘤的局部肿瘤控制情况有所改善。然而，大型葡萄膜黑色素瘤转移导致的5年死亡率仍然很高。最近，孤立肝灌注疗法和化疗在提高转移灶生存率方面均取得了令人鼓舞的结果。因此，早期筛查，尤其是针对肝转移的筛查，变得势在必行。