非典型神经细胞瘤不完全切除术后放疗的剂量效应关系

Dose-effect relationship for radiotherapy after incomplete resection of atypical neurocytomas.

作者信息

Rades Dirk, Fehlauer Fabian, Ikezaki Kiyonobu, Schild Steven E

机构信息

Department of Radiation Oncology, University Hospital Hamburg-Eppendorf, Hamburg, Germany.

出版信息

Radiother Oncol. 2005 Jan;74(1):67-9. doi: 10.1016/j.radonc.2004.08.008.

DOI:10.1016/j.radonc.2004.08.008

PMID:15683672

Abstract

Neurocytomas with atypical histology or high proliferation activity are named atypical. All reported cases were reviewed. After incomplete resection, radiotherapy improved local-control (P<0.001) and survival (P=0.02). Doses (EQD2) >54 Gy were associated with better 5-year local control (84% versus 55%, P=0.05) and 5-year-survival (84% versus 65%, P=0.18) than doses < or =54 Gy.

摘要

具有非典型组织学或高增殖活性的神经细胞瘤被称为非典型性神经细胞瘤。对所有报告的病例进行了回顾。不完全切除术后，放疗改善了局部控制情况（P<0.001）和生存率（P=0.02）。与剂量≤54 Gy相比，剂量（等效剂量2）>54 Gy与更好的5年局部控制率（84%对55%，P=0.05）和5年生存率（84%对65%，P=0.18）相关。