Pajala M, Heikkinen M, Hintikka J
Department of Internal Medicine, Kuopio University Hospital, Kuopio, Finland.
Aliment Pharmacol Ther. 2005 Feb 1;21(3):277-81. doi: 10.1111/j.1365-2036.2005.02296.x.
It has been argued that patients with functional gastrointestinal disorders have mental disorders more often than healthy controls and patients with organic disease. Most studies surveying psychological factors at the population level have relied on symptom questionnaires to diagnose functional dyspepsia. However, the symptom patterns alone are unable to adequately discriminate organic from functional dyspepsia.
To evaluate the frequency of mental distress in primary care patients with organic or functional dyspepsia and compare the findings with a sample of the Finnish general population.
Four-hundred consecutive, unselected dyspeptic patients were referred for upper gastrointestinal endoscopy and other diagnostic examinations. All patients compiled a self-administered questionnaire including the 12-item General Health Questionnaire to detect cases of recent mental disorders.
The prevalence of mental distress among patients with functional and organic dyspepsia was 38 and 36.4% respectively. The sex- and age-adjusted risk of having mental distress was nearly fourfold higher among patients with dyspepsia than in the general population.
Mental distress is common among patients with functional or organic dyspepsia. Nevertheless, there is no difference between patients with functional or organic dyspepsia in the prevalence or risk of mental distress.
有人认为，功能性胃肠病患者比健康对照者以及患有器质性疾病的患者更常出现精神障碍。大多数在人群层面调查心理因素的研究都依赖症状问卷来诊断功能性消化不良。然而，仅凭症状模式无法充分区分器质性消化不良和功能性消化不良。
评估基层医疗中患有器质性或功能性消化不良患者的精神困扰发生率，并将结果与芬兰普通人群样本进行比较。
连续400例未经挑选的消化不良患者被转诊进行上消化道内镜检查和其他诊断性检查。所有患者填写一份自填式问卷，其中包括用于检测近期精神障碍病例的12项一般健康问卷。
功能性和器质性消化不良患者中精神困扰的患病率分别为38%和36.4%。经性别和年龄调整后，消化不良患者出现精神困扰的风险比普通人群高近四倍。
精神困扰在功能性或器质性消化不良患者中很常见。然而，功能性或器质性消化不良患者在精神困扰的患病率或风险方面没有差异。
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