Sakagami Junichi, Sogame Yoshio, Kataoka Keisho, Kanemitsu Daisuke, Takada Ryusuke, Ito Reiko, Motoyoshi Tomoko, Mitsufuji Shoji, Okanoue Takeshi, Akioka Kiyokazu, Okamoto Masahiko, Yoshimura Norio
Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, 465 Kajiicho Hirokoji Kamigyoku, Kyoto 602-8566, Japan.
J Gastroenterol. 2005 Jan;40(1):98-103. doi: 10.1007/s00535-004-1500-0.
Kaposi's sarcoma is an uncommon neoplasm that occasionally involves the gastrointestinal tract in immunosuppressed individuals. Infection with human herpes virus 8 is known to be necessary for developing all forms of Kaposi's sarcoma. We report a renal transplant recipient who developed visceral Kaposi's sarcoma 18 months after the transplantation. In Oriental countries, the incidence of Kaposi's sarcoma is extremely low, and this is the first case of Kaposi's sarcoma arising from a transplant recipient in Japan. Standard forceps biopsies of the gastric lesions failed to make the correct diagnosis. However, endoscopic resection successfully led to the correct diagnosis of Kaposi's sarcoma and herpes simplex virus 8 infection as well. This is the first report of a patient with visceral Kaposi's sarcoma who underwent endoscopic resection that reliably confirmed histological diagnosis and the viral genome at the same time.
卡波西肉瘤是一种罕见的肿瘤，偶尔会累及免疫抑制个体的胃肠道。已知感染人类疱疹病毒8是发生各种形式卡波西肉瘤的必要条件。我们报告一例肾移植受者，在移植后18个月发生了内脏卡波西肉瘤。在东方国家，卡波西肉瘤的发病率极低，这是日本首例由移植受者发生的卡波西肉瘤。对胃部病变进行标准钳取活检未能做出正确诊断。然而，内镜下切除成功地做出了卡波西肉瘤及单纯疱疹病毒8感染的正确诊断。这是首例接受内镜下切除的内脏卡波西肉瘤患者的报告，该切除同时可靠地证实了组织学诊断和病毒基因组。
Zotero 插件