Ebe K, Nagai T, Wakiya Y, Igarashi T
Department of Cardiology, Nagaoka Red Cross Hospital.
Kokyu To Junkan. 1992 Apr;40(4):403-6.
A case is reported of a 56-year-old man with primary coronary dissection presenting as sudden death due to aortic rupture and cardiac tamponade. He was admitted because of loss of consciousness and chest pain. ECG showed complete atrioventricular block and myocardial infarction. Coronary angiography demonstrated coronary dissection and total obstruction of right coronary artery (RCA). Intracoronary injection of urokinase was not effective for recanalization of RCA. He died suddenly two days later. At autopsy, the proximal site of the ascending aorta was dissected locally and had ruptured into a pericardial space. RCA was torn off. The perivascular area around the torn coronary artery communicated with the dissecting space of the ascending aorta. Histologically, no degeneration or infiltration of inflammatory cells was observed in the media of the aorta and the right coronary artery. Histological change was observed only at the media of the torn site of the coronary artery. The thickness of the media was about half of that at the other site of the coronary artery. This is the third case reported in world medical literature of primary coronary dissection presenting as cardiac tamponade.
报道了一例56岁男性原发性冠状动脉夹层,表现为因主动脉破裂和心脏压塞导致的猝死。他因意识丧失和胸痛入院。心电图显示完全性房室传导阻滞和心肌梗死。冠状动脉造影显示冠状动脉夹层和右冠状动脉(RCA)完全阻塞。冠状动脉内注射尿激酶对RCA再通无效。两天后他突然死亡。尸检时,升主动脉近端局部夹层并破裂进入心包腔。RCA被撕裂。撕裂冠状动脉周围的血管周围区域与升主动脉的夹层空间相通。组织学上,在主动脉和右冠状动脉的中膜未观察到炎症细胞的变性或浸润。仅在冠状动脉撕裂部位的中膜观察到组织学改变。该部位中膜厚度约为冠状动脉其他部位的一半。这是世界医学文献中报道的第三例以心脏压塞为表现的原发性冠状动脉夹层病例。