van Lenthe F J, Borrell L N, Costa G, Diez Roux A V, Kauppinen T M, Marinacci C, Martikainen P, Regidor E, Stafford M, Valkonen T
Department of Public Health, Erasmus Medical Centre, Rotterdam, Rotterdam, The Netherlands.
J Epidemiol Community Health. 2005 Mar;59(3):231-7. doi: 10.1136/jech.2004.022574.
Studies have shown that living in more deprived neighbourhoods is related to higher mortality rates, independent of individual socioeconomic characteristics. One approach that contributes to understanding the processes underlying this association is to examine whether the relation is modified by the country context. In this study, the size of the association between neighbourhood unemployment rates and all cause mortality was compared across samples from six countries (United States, Netherlands, England, Finland, Italy, and Spain).
Data from three prospective cohort studies (ARIC (US), GLOBE (Netherlands), and Whitehall II (England)) and three population based register studies (Helsinki, Turin, Madrid) were analysed. In each study, neighbourhood unemployment rates were derived from census, register based data. Cox proportional hazard models, taking into account the possible correlation of outcomes among people of the same neighbourhood, were used to assess the associations between neighbourhood unemployment and all cause mortality, adjusted for education and occupation at the individual level.
In men, after adjustment for age, education, and occupation, living in the quartile of neighbourhoods with the highest compared with the lowest unemployment rates was associated with increased hazards of mortality (14%-46%), although for the Whitehall II study associations were not statistically significant. Similar patterns were found in women, but associations were not statistically significant in two of the five studies that included women.
Living in more deprived neighbourhoods is associated with increased all cause mortality in the US and five European countries, independent of individual socioeconomic characteristics. There is no evidence that country substantially modified this association.
研究表明,生活在贫困程度更高的社区与更高的死亡率相关,且不受个体社会经济特征的影响。有助于理解这种关联背后过程的一种方法是考察这种关系是否会因国家背景而有所不同。在本研究中,比较了来自六个国家(美国、荷兰、英国、芬兰、意大利和西班牙)的样本中社区失业率与全因死亡率之间关联的大小。
分析了三项前瞻性队列研究(美国的ARIC研究、荷兰的GLOBE研究和英国的白厅II研究)以及三项基于人群登记的研究(赫尔辛基、都灵、马德里)的数据。在每项研究中,社区失业率均源自人口普查和基于登记的数据。使用Cox比例风险模型,并考虑到同一社区人群中结局可能存在的相关性,来评估社区失业率与全因死亡率之间的关联,并在个体层面上对教育和职业进行了调整。
在男性中,在对年龄、教育和职业进行调整后,与失业率最低的社区相比,生活在失业率最高的社区四分位数中的人群死亡率风险增加(14%-46%),尽管对白厅II研究而言,这种关联在统计学上并不显著。在女性中也发现了类似的模式,但在纳入女性的五项研究中的两项中,这种关联在统计学上并不显著。
在美国和五个欧洲国家,生活在贫困程度更高的社区与全因死亡率增加相关,且不受个体社会经济特征的影响。没有证据表明国家会显著改变这种关联。