Volkmar Fred, Chawarska Kasia, Klin Ami
Child Study Center, Yale University School of Medicine, New Haven, CT 06520, USA.
Annu Rev Psychol. 2005;56:315-36. doi: 10.1146/annurev.psych.56.091103.070159.
Although initially described as an inborn disorder of affective contact, information on autism as it exists in infants has been limited. Delays in diagnosis, lack of information about the condition, and reliance on retrospective research strategies have been problematic. An awareness of the increased risk for siblings is now allowing the development of new, prospective approaches. Consistent with Kanner's original hypothesis, the available information strongly suggests a fundamental difficulty in the earliest social processes, which, in turn, impacts many other areas of development. New approaches to screening have lowered the age of initial diagnosis; this presents new challenges for early intervention. Directions for future research are highlighted.
尽管最初将自闭症描述为情感交流方面的先天性障碍,但关于婴儿期自闭症的现有信息一直有限。诊断延迟、对该病症缺乏了解以及依赖回顾性研究策略一直存在问题。如今,意识到自闭症患儿兄弟姐妹患病风险增加,这促使新的前瞻性研究方法得以发展。与坎纳最初的假设一致,现有信息有力地表明,自闭症在早期社交过程中存在根本性困难,进而影响到许多其他发展领域。新的筛查方法降低了首次诊断的年龄;这给早期干预带来了新挑战。文中还强调了未来的研究方向。