Williams N S, Giordano P, Dvorkin L S, Huang A, Hetzer F H, Scott S M
Center for Academic Surgery, The Royal London Hospital, Fourth Floor Alexandra Wing, London E1 1BB, Whitechapel, United Kingdom.
Dis Colon Rectum. 2005 Feb;48(2):307-16. doi: 10.1007/s10350-004-0806-6.
The Délorme's operation for rectal prolapse is a safe procedure but has a high recurrence rate. We aimed to develop an operation akin to it, but designed to reduce this deficit.
Thirty-one consecutive patients with rectal prolapse were included in the study. Initially, a conventional Délorme's procedure was performed and sutures or strips of Gore-Tex were attached circumferentially to the apex of the prolapse, tunneled subcutaneously, and anchored to the external surface of the pelvis. Subsequently, the procedure was modified. Acellular porcine collagen strips were used and buried within the apex without plication of the denuded rectal musculature. Patients were formally assessed preoperatively and four months postoperatively by symptom and quality of life questionnaires and subsequently by regular clinical review.
In the Gore-Tex group (N = 11; males:females = 10:1; mean age, 61 years) three patients underwent suture repair and eight had strip fixation. All suture repairs developed sepsis and one patient had a recurrence. Seven of the strip fixations (88 percent) developed sepsis that resulted in implant extrusion. There was one full-thickness and one mucosal recurrence after a median follow-up of 25 months. In the collagen group (N = 20; males:females = 2:18; mean age, 63 years), sepsis occurred in four patients, requiring surgical intervention in one patient (5 percent) (cf Gore-Tex group, P = 0.002). There was one mucosal and three full-thickness (15 percent) recurrences after a median follow-up of 14 months (cf Gore-Tex group, P = not significant). Significant improvements in symptom and quality of life scores were recorded in both groups at four months.
A new, minimally invasive perineal procedure for rectal prolapse has been developed and initial data testify to its relative safety provided collagen is used. It remains to be seen whether long-term recurrence rates will be lower than those of conventional perineal procedures.
用于直肠脱垂的德洛姆手术是一种安全的术式,但复发率较高。我们旨在开发一种与之类似但旨在减少这一缺陷的手术。
31例连续性直肠脱垂患者纳入本研究。最初,实施传统的德洛姆手术,将缝线或戈尔特斯条带沿脱垂顶端环形附着,经皮下隧道引出并固定于骨盆外表面。随后,对该手术进行改良。使用脱细胞猪胶原条带并埋入顶端,不对裸露的直肠肌肉组织进行折叠。术前及术后4个月通过症状和生活质量问卷对患者进行正式评估,随后进行定期临床复查。
在戈尔特斯组(N = 11;男:女 = 10:1;平均年龄61岁),3例患者接受缝线修复,8例进行条带固定。所有缝线修复均发生感染,1例患者复发。88%(7例)的条带固定发生感染,导致植入物挤出。中位随访25个月后,出现1例全层复发和1例黏膜复发。在胶原组(N = 20;男:女 = 2:18;平均年龄63岁),4例患者发生感染,1例患者(5%)需要手术干预(与戈尔特斯组相比,P = 0.002)。中位随访14个月后,出现1例黏膜复发和3例全层复发(15%)(与戈尔特斯组相比,P无显著性差异)。两组在术后4个月时症状和生活质量评分均有显著改善。
已开发出一种用于直肠脱垂的新型微创会阴手术,初步数据证明使用胶原时其相对安全。长期复发率是否低于传统会阴手术还有待观察。