Deresinski Stan
Division of Infectious Disease and Geographic Medicine, Department of Medicine, Stanford University, Stanford, CA, USA.
Clin Infect Dis. 2005 Feb 15;40(4):562-73. doi: 10.1086/427701. Epub 2005 Jan 24.
Methicillin-resistant Staphylococcus aureus, first identified just over 4 decades ago, has undergone rapid evolutionary changes and epidemiologic expansion. It has spread beyond the confines of health care facilities, emerging anew in the community, where it is rapidly becoming a dominant pathogen. This has led to an important change in the choice of antibiotics in the management of community-acquired infections and has also led to the development of novel antimicrobials.
耐甲氧西林金黄色葡萄球菌于40多年前首次被发现，此后经历了快速的进化变化和流行病学传播。它已扩散到医疗机构范围之外，在社区中重新出现，且正迅速成为主要病原体。这导致了社区获得性感染治疗中抗生素选择的重大变化，也促使了新型抗菌药物的研发。
