Aström H, Holmgren A, Jonsson B
Br Heart J. 1979 Apr;41(4):477-80. doi: 10.1136/hrt.41.4.477.
Blood volume was measured in 60 consecutive male patients with disabling angina pectoris undergoing preoperative investigation for coronary bypass surgery. Of these patients, 58 had a lower blood volume than predicted. There was a decrease in blood volume of 21% (1.3 litres) from the predicted normal value (P less than 0.001). Seventeen per cent of the patients were on diuretics, 30% were on digitalis, and 48% were on beta-blocking drugs at the time of the study. There was no correlation between this medical treatment and the deviation in blood volume. In patients without signs of myocardial insufficiency the decrease in blood volume was most prominent, while in those with an enlarged heart and a raised left ventricular preload (at rest) the deviation was less.
对60例因严重心绞痛而接受冠状动脉搭桥手术术前检查的连续男性患者进行了血容量测量。在这些患者中，58例的血容量低于预测值。血容量比预测的正常值减少了21%（1.3升）（P<0.001）。研究时，17%的患者正在服用利尿剂，30%正在服用洋地黄，48%正在服用β受体阻滞剂。这种药物治疗与血容量偏差之间没有相关性。在没有心肌功能不全迹象的患者中，血容量减少最为明显，而在心脏扩大且左心室前负荷（静息时）升高的患者中，偏差较小。
