Müller-Bierl Bernd, Graf Hansjörg, Steidle Günter, Schick Fritz
Diagnostics Radiology, University Hospital, Tuebingen, Bader-Wuertemberg 72076, Germany.
Med Phys. 2005 Jan;32(1):76-84. doi: 10.1118/1.1828674.
In minimally invasive procedures guided by magnetic resonance (MR) imaging instruments usually are made of titanium or titanium alloys (e.g., nitinol), because other more MR-compatible materials often cannot provide sufficient mechanical properties. Artifacts depending on susceptibility arise in MR images due to incorrect spatial encoding and intravoxel dephasing and thereby hamper the surgeon's view onto the region of interest. To overcome the artifact problem, compensation of the paramagnetic properties by diamagnetic coating or filling of the instruments has been proposed in the literature. We used a numerical modeling procedure to estimate the effect of compensation. Modeling of the perturbation of the static magnetic field close to the instruments reflects the underlying problem and is much faster and cost efficient than manufacturing prototypes and measuring artifact behavior of these prototypes in the MR scanner. A numerical model based on the decomposition of the susceptibility distribution in elementary dipoles was developed by us. The program code was written object oriented to allow for both maximum computational speed and minimum random access memory. We used System International units throughout the modeling for the magnetic field, allowing absolute quantification of the magnetic field disturbance. The field outside a simulated needlelike instrument, modeled by a paramagnetic cylinder (out of titan, chi =181.1) of length 8.0 mm and of diameter 1.0 mm, coated with a diamagnetic layer (out of bismuth, chi=-165.0) of thickness 0, 0.1, 0.2, 0.3, and 0.4 mm, was found to be best compensated if the cross-sectional area of the cylinder, multiplied by the absolute susceptibility value of the cylinder material, is equal to the cross-sectional area of the coating, multiplied by the absolute susceptibility value of the coating material. At the extremity of the coated cylinder an uncompensated field distortion was found to remain. We studied various tip shapes and geometries using our computational model: Suitable diamagnetic coating or filling of paramagnetic instruments clearly reduced tip artifacts and diminished the dependency of artifact size on orientation of the instrument with respect to B0 in the numerical studies. We verified the results of the simulations by measuring coated and uncoated titanium wires in a 1.5 T MR scanner.
在由磁共振(MR)成像引导的微创手术中,器械通常由钛或钛合金(如镍钛诺)制成,因为其他更具MR兼容性的材料往往无法提供足够的机械性能。由于不正确的空间编码和体素内去相位,MR图像中会出现取决于磁化率的伪影,从而妨碍外科医生观察感兴趣区域。为了克服伪影问题,文献中提出了通过抗磁性涂层或填充器械来补偿顺磁性特性的方法。我们使用了一种数值建模程序来估计补偿效果。对靠近器械的静磁场扰动进行建模反映了潜在问题,并且比制造原型并在MR扫描仪中测量这些原型的伪影行为要快得多且成本效益更高。我们开发了一个基于基本偶极子中磁化率分布分解的数值模型。程序代码采用面向对象编写,以实现最大计算速度和最小随机存取存储器。在整个建模过程中,我们对磁场使用国际单位制,从而能够对磁场干扰进行绝对量化。对于一个模拟的针状器械,其由长度为8.0毫米、直径为1.0毫米的顺磁性圆柱体(钛材质,χ = 181.1)建模,表面涂有厚度为0、0.1、0.2、0.3和0.4毫米的抗磁性层(铋材质,χ = -165.0),研究发现,如果圆柱体的横截面积乘以圆柱体材料的绝对磁化率值等于涂层的横截面积乘以涂层材料的绝对磁化率值,那么该器械外部的磁场能得到最佳补偿。在涂覆圆柱体的末端发现仍存在未补偿的场畸变。我们使用计算模型研究了各种尖端形状和几何结构:在数值研究中,合适的抗磁性涂层或对顺磁性器械进行填充能明显减少尖端伪影,并降低伪影大小对器械相对于B0方向的依赖性。我们通过在1.5 T MR扫描仪中测量涂覆和未涂覆的钛丝来验证模拟结果。