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浅表扩散型胆管癌

Superficially spreading cholangiocarcinoma.

作者信息

Abe Motoki, Kondo Satoshi, Hirano Satoshi, Ambo Yoshiyasu, Tanaka Eiichi, Saito Katsunori, Morikawa Toshiaki, Okushiba Shunichi, Katoh Hiroyuki

机构信息

Department of Surgical Oncology, Division of Cancer Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan.

出版信息

Int J Gastrointest Cancer. 2005;35(1):89-94. doi: 10.1385/IJGC:35:1:089.

Abstract

Cholangiocarcinoma of a raised, elevated type, not an infiltrative type, may be accompanied with superficial spread in the contiguous mucosa. We report a case of an extrahepatic cholangiocarcinoma that showed a specific cholangiographic finding of extensive superficial spread. The patient was a 62-yr-old man. Cholangiography revealed an elevated lesion in the middle of the bile duct, which was surrounded by irregularity of the bile duct wall extensively. We accurately diagnosed the tumor extent by percutaneous transhepatic cholangioscopy and achieved radical resection without hepatic resection. The margins were tumor-negative by microscopy. In conclusions, it is important to accurately diagnose the extent of superficial spread preoperatively by cholangioscopy and biopsy, and decide the resecting lines to make margins tumor-negative.

摘要

隆起型而非浸润型的胆管癌可能伴有邻近黏膜的浅表扩散。我们报告一例肝外胆管癌,其显示出广泛浅表扩散的特定胆管造影表现。患者为一名62岁男性。胆管造影显示胆管中部有一隆起病变,周围胆管壁广泛不规则。我们通过经皮经肝胆管镜准确诊断了肿瘤范围,并在未进行肝切除的情况下实现了根治性切除。显微镜检查切缘无肿瘤。总之,术前通过胆管镜检查和活检准确诊断浅表扩散范围并确定切除线以使切缘无肿瘤是很重要的。

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