发作期微笑在儿童癫痫中偏向右侧半球。

Ictal smile lateralizes to the right hemisphere in childhood epilepsy.

作者信息

Fogarasi András, Janszky József, Siegler Zsuzsanna, Tuxhorn Ingrid

机构信息

Epilepsie-Zentrum Bethel, Bielefeld, Maraweg, Germany.

出版信息

Epilepsia. 2005 Mar;46(3):449-51. doi: 10.1111/j.0013-9580.2005.47704.x.

DOI:10.1111/j.0013-9580.2005.47704.x

PMID:15730544

Abstract

PURPOSE

To analyze the localizing and lateralizing value of ictal smile (IS) in childhood epilepsy.

METHODS

Incidence of IS in 309 videotaped seizures of 114 consecutive patients younger than 12 years with refractory frontal, temporal, or posterior cortex epilepsy were assessed.

RESULTS

Among patients with right-sided epileptogenic zone, 12 (21%) of 57 had IS, whereas in patients with left-sided epilepsy, IS occurred only in one patient (1.8%; p < 0.01, chi(2) test). The incidence of IS was 11%, 3%, and 26% in the frontal, temporal, and posterior cortex subgroups, respectively. Logistic regression revealed that the localization of the epileptogenic region in the posterior cortex (p < 0.01), focal cortical dysplasia etiology (p = 0.012), and right-sided lateralization (p = 0.025) were independently associated with the presence of IS.

CONCLUSIONS

Childhood IS lateralizes to the right hemisphere and localizes more frequently in the posterior cortex epilepsy.

摘要

目的

分析发作期微笑（IS）在儿童癫痫中的定位及定侧价值。

方法

对114例连续的12岁以下难治性额叶、颞叶或后皮质癫痫患者的309次录像发作中IS的发生率进行评估。

结果

在右侧致痫区患者中，57例中有12例（21%）出现IS，而在左侧癫痫患者中，仅1例（1.8%）出现IS（p<0.01，卡方检验）。额叶、颞叶和后皮质亚组中IS的发生率分别为11%、3%和26%。逻辑回归显示，后皮质致痫区的定位（p<0.01）、局灶性皮质发育异常病因（p = 0.012）和右侧定侧（p = 0.025）与IS的存在独立相关。