Wilson Kumanan, Busse Jason W, Gilchrist Amy, Vohra Sunita, Boon Heather, Mills Edward
Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
Pediatrics. 2005 Mar;115(3):e338-43. doi: 10.1542/peds.2004-1901.
The use of complementary and alternative medicine (CAM) has grown substantially in North America and has drawn the attention of conventional-medicine practitioners. Conventional-medicine practitioners have expressed concern about the potential for unregulated CAM therapies to cause harm, the sometimes-uncertain cost-benefit ratios associated with these therapies, and the possibility that some CAM providers might advise against established conventional therapies, such as vaccination. These concerns are heightened with respect to the pediatric use of CAM products. To address this issue, we conducted a systematic audit of pediatric and adolescent case files at a large, college-based, Canadian naturopathic teaching clinic. We specifically sought to describe the demographic characteristics, reasons for presentation, use of CAM products, and vaccinations status of children presenting for naturopathic assessment. We also determined factors associated with the use of CAM products and vaccination status.
We identified all charts for children (<18 years of age) who presented to the Robert Schad Naturopathic Clinic, the teaching clinic of the Canadian College of Naturopathic Medicine, between February 1 and May 31, 2002. Data were abstracted directly from the standardized patient intake forms and from clinical notes recorded during the patient's initial visit to the clinic. The following data were obtained: age, gender, chief presenting complaints reported by parents, CAM product use at presentation, vaccination status, and reactions to vaccination. We conducted logistic regression analyses to identify factors associated with both CAM product use and vaccination status.
A total of 482 charts were identified. The mean age of patients was 6.5 years (95% confidence interval [CI]: 1.6-11.4 years). The ratio of female subjects to male subjects was 1.09:1 (248:227). The most common reasons for presentation were skin disorders (23%), gastrointestinal complaints (17%), and psychiatric/behavioral disorders (15%). Thirty-five percent of children were using CAM products at presentation (21.2% when both vitamins and minerals were excluded). Vitamins were the most commonly used products (34.6%), followed by herbal remedies (14.9%), oil blends/fats (7.2%), minerals (5.6%), probiotics (4.5%), and homeopathic remedies (3.7%). Of charts with vaccination information, 8.9% indicated that children had not been vaccinated; possible vaccine-associated adverse events were reported for 27% of those who had been vaccinated. Partial or unvaccinated status was associated with younger age, attending the Canadian College of Naturopathic Medicine for advice regarding vaccination, and greater use of CAM products. CAM product use was associated with unvaccinated or partially vaccinated status (odds ratio [OR]: 2.86; 95% CI: 1.46-5.63), presenting with poor energy or fatigue (OR: 3.36; 95% CI: 1.00-11.26), or presenting with throat or sinus infections (OR: 4.06; 95% CI: 1.23-13.04).
Children present for naturopathic assessment for diverse reasons, are high-level consumers of CAM products, and have lower rates of vaccination than population averages. The conventional-medicine community should work with naturopaths to address public health concerns in this population.
补充和替代医学(CAM)在北美的使用显著增加,已引起传统医学从业者的关注。传统医学从业者对未经监管的CAM疗法可能造成伤害、这些疗法有时不确定的成本效益比,以及一些CAM从业者可能建议反对既定的传统疗法(如疫苗接种)表示担忧。对于儿科使用CAM产品,这些担忧更为突出。为解决这一问题,我们对加拿大一所大型的、以大学为基础的自然疗法教学诊所的儿科和青少年病例档案进行了系统审查。我们特别试图描述前来接受自然疗法评估的儿童的人口统计学特征、就诊原因、CAM产品使用情况和疫苗接种状况。我们还确定了与使用CAM产品和疫苗接种状况相关的因素。
我们识别出2002年2月1日至5月31日期间就诊于加拿大自然疗法学院教学诊所罗伯特·沙德自然疗法诊所的所有18岁以下儿童的病历。数据直接从标准化的患者入院表格以及患者初次就诊时记录的临床笔记中提取。获取了以下数据:年龄、性别、家长报告的主要就诊主诉、就诊时的CAM产品使用情况、疫苗接种状况以及对疫苗接种的反应。我们进行了逻辑回归分析,以确定与CAM产品使用和疫苗接种状况相关的因素。
共识别出482份病历。患者的平均年龄为6.5岁(95%置信区间[CI]:1.6 - 11.4岁)。女性与男性的比例为1.09:1(248:227)。最常见的就诊原因是皮肤疾病(23%)、胃肠道疾病(17%)以及精神/行为障碍(15%)。35%的儿童在就诊时使用CAM产品(排除维生素和矿物质后为21.2%)。维生素是最常用的产品(34.6%),其次是草药(14.9%)、油类混合物/脂肪(7.2%)、矿物质(5.6%)、益生菌(4.5%)和顺势疗法药物(3.7%)。在有疫苗接种信息的病历中,8.9%表明儿童未接种疫苗;在已接种疫苗的儿童中,27%报告了可能与疫苗相关的不良事件。部分接种或未接种疫苗的状况与年龄较小、前往加拿大自然疗法学院咨询疫苗接种建议以及更多地使用CAM产品相关。使用CAM产品与未接种或部分接种疫苗的状况相关(优势比[OR]:2.86;95%CI:1.46 - 5.63),表现为精力不足或疲劳(OR:3.36;95%CI:1.00 - 11.26),或表现为喉咙或鼻窦感染(OR:4.06;95%CI:1.23 - 13.04)。
儿童因多种原因前来接受自然疗法评估,是CAM产品的高消费群体,且疫苗接种率低于总体平均水平。传统医学界应与自然疗法从业者合作,解决该人群中的公共卫生问题。