Villacastín J P, Almendral J, Arenal A, Ormaetxe J, Esteban E, Alberca T, Maroto C, Delcán J L
Laboratorio de Electrofisiología, Hospital General Gregorio Marañón, Madrid.
Rev Esp Cardiol. 1992 Mar;45(3):175-82.
Sixteen consecutive patients (5 males and 11 females) aged 40 +/- 22 years suffering for spontaneous symptomatic arrhythmias underwent attempted transcatheter ablation of an atrioventricular accessory pathway using radiofrequency current. Five patients had the WPW syndrome. The Kent bundle was located in the left free wall in 14 patients, in the right anteroseptal region in one patient and in the posteroseptal zone in one patient. A 7F catheter (Polaris, Mansfield) with a 4 mm2 distal electrode, was used for ablation positioned on the left atrioventricular annulus in the 13 patients with left free wall accessory pathways or at the right atrium in the two patients with right accessory pathways. Without general anesthesia, a mean of 12 +/- 9 applications of radiofrequency current were delivered between the large tip electrode and a large skin patch positioned on the left posterior chest. By using radiofrequency current, a successful clinical outcome was achieved in 14 of 16 patients (87%). In patients with concealed accessory pathways, accessory conduction was abolished in 10 of 11 patients, in 8 patients in the first radiofrequency session and in two other patients in a successful second procedure. In the 5 patients with the WPW syndrome, the anterograde conduction disappeared after the procedure but the retrograde conduction remained, although deteriorated, in 2 patients. One patient developed uncomplicated tibioperoneal thrombophlebitis and in 2 cases an elevated concentration of creatine kinase value was found. In one female patient with a concealed accessory pathway, the Kent bundle conduction reappeared 3 months after the procedure and was ablated in a second session.(ABSTRACT TRUNCATED AT 250 WORDS)
16例年龄40±22岁、患有自发性症状性心律失常的连续患者(5例男性和11例女性)接受了经导管使用射频电流消融房室旁道的尝试。5例患者患有预激综合征(WPW综合征)。14例患者的肯特束位于左游离壁,1例位于右前间隔区域,1例位于后间隔区。对于13例左游离壁旁道患者,使用带有4 mm²远端电极的7F导管(北极星,曼斯菲尔德)置于左房室环进行消融;对于2例右旁道患者,则置于右心房。在未进行全身麻醉的情况下,在大尖端电极与置于左后胸部的大皮肤贴片之间平均施加12±9次射频电流。通过使用射频电流,16例患者中有14例(87%)取得了成功的临床结果。在隐匿性旁道患者中,11例患者中有10例旁道传导被消除,8例在首次射频治疗时消除,另外2例在第二次成功手术时消除。在5例WPW综合征患者中,术后前向传导消失,但2例患者的逆向传导仍存在,尽管有所恶化。1例患者发生了无并发症的胫腓静脉血栓性静脉炎,2例患者发现肌酸激酶值升高。1例患有隐匿性旁道的女性患者,术后3个月肯特束传导重新出现,并在第二次治疗中被消融。(摘要截短至250字)