玛丽·布罗德富特·沃克（1888 - 1974）：重症肌无力领域的一项历史性发现。

Mary Broadfoot Walker (1888-1974): a historic discovery in myasthenia gravis.

作者信息

Pearce J M S

机构信息

Emeritus Consultant Neurologist, Department of Neurology, Hull Royal Infirmary, Hull, UK.

出版信息

Eur Neurol. 2005;53(1):51-3. doi: 10.1159/000084268. Epub 2005 Mar 1.

DOI:10.1159/000084268

PMID:15746548

Abstract

As a clinical entity, myasthenia gravis was not recognized until Samuel Wilks in 1877 described bulbar and peripheral muscular weakness. In the Lancet of June 2, 1934, the remarkable discovery of physostigmine treatment by Dr. Mary Walker was published, which was to become the mainstay of symptomatic treatment. A quiet and modest physician, she laboured with considerable success under many obstacles in her work and career.

摘要

作为一种临床病症，重症肌无力直到1877年塞缪尔·威尔克斯描述了延髓和周围肌肉无力才被认识。1934年6月2日，玛丽·沃克医生关于毒扁豆碱治疗的重大发现发表在《柳叶刀》杂志上，这一发现后来成为了对症治疗的主要手段。她是一位安静谦逊的医生，在工作和职业生涯中克服了重重困难，取得了相当大的成功。