Pandey Arushi, George Jiji, Rao Nirmala N
Department of Oral Pathology, and Microbiology, Manipal College of Dental Sciences, Manipal.
Indian J Dent Res. 2004 Apr-Jun;15(2):74-7.
Mucormycosis is a rare, often fatal opportunistic infection caused by a saprophytic fungus belonging to a class of Phycomycetes. It is characterized by its unrelenting progression towards vital organs with marked propensity towards arterial wall by direct extension producing vascular thrombosis leading to ischaemic necrosis. In normal circumstances the saprophytes are not pathogenic but represent opportunist-requiring impairments in patient's resistance to disease. If not treated the disease may prove fatal. We report a case of Mucormycosis with extensive necrosis of the maxilla in a 57-year-old patient suffering from uncontrolled diabetes with ketoacidosis.
毛霉菌病是一种罕见的、通常致命的机会性感染,由属于接合菌纲的腐生真菌引起。其特点是向重要器官持续进展,明显倾向于通过直接蔓延侵犯动脉壁,导致血管血栓形成,进而引起缺血性坏死。在正常情况下,腐生菌不具有致病性,但在患者抗病能力受损时成为机会致病菌。若不治疗,该病可能会致命。我们报告一例57岁患有未控制的糖尿病伴酮症酸中毒的患者发生上颌骨广泛坏死的毛霉菌病病例。