Larionov S, König R, Urbach H, Sassen R, Elger C E, Bien C G
Department of Neuropathology, University of Bonn, Bonn, Germany.
Neurology. 2005 Mar 8;64(5):885-7. doi: 10.1212/01.WNL.0000152895.23010.52.
Rasmussen encephalitis (RE) is regarded as a unihemispheric disease. Serial three-dimensional MRIs of 18 patients under immunotherapy were analyzed volumetrically and planimetrically. Median volume loss was significantly higher in the affected than in the unaffected hemispheres (29.9 cm3/y vs 6.8 cm3/y). Correlation of the planimetrically and volumetrically assessed hemispheric ratios (HRs) was significant. The results support the concept of RE as a basically unilateral disease. Planimetric HR assessment is valid and time efficient.
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