意大利威尼托大区的“绿色通道”作为疫苗安全监测的典范。

The "Green Channel" of the Veneto region as a model for vaccine safety monitoring in Italy.

作者信息

Zanoni G, Ferro A, Valsecchi M, Tridente G

机构信息

Immunology Unit, Department of Pathology, University of Verona, Policlinico G.B. Rossi, 37134 Verona, Italy.

出版信息

Vaccine. 2005 Mar 18;23(17-18):2354-8. doi: 10.1016/j.vaccine.2005.01.021.

DOI:10.1016/j.vaccine.2005.01.021

PMID:15755627

Abstract

Modern vaccinology and public health organizations need to satisfy an increased safety demand. Therefore, to improve adverse events following immunization (AEFIs) surveillance systems, some countries have established clinical evaluation centers for AEFI assessment and management of at risk individuals. In the Veneto region of Italy, the Green Channel operates through a counselling service for subjects with prior AEFI or with suspected contraindications to vaccine administration, and a surveillance system of the AEFIs reported in the region. Updated data on 753 consultations and 3023 AEFI analyses are discussed together with the opportunity to include the Green Channel model as part of an international vaccine safety network.

摘要

现代疫苗学和公共卫生组织需要满足日益增长的安全需求。因此，为改进免疫接种后不良事件（AEFIs）监测系统，一些国家已设立临床评估中心，用于对有风险个体进行AEFI评估和管理。在意大利威尼托地区，绿色通道通过为既往有AEFI或疑似有疫苗接种禁忌的受试者提供咨询服务以及对该地区报告的AEFIs进行监测系统来运作。本文讨论了753次咨询和3023次AEFI分析的最新数据，以及将绿色通道模式纳入国际疫苗安全网络一部分的可能性。