Combinatorial libraries - from solution to 2D microarrays.
作者信息
Díaz-Mochón Juan José, Bialy Laurent, Keinicke Lise, Bradley Mark
机构信息
School of Chemistry, University of Southampton, Southampton, UK SO17 1BJ.
出版信息
Chem Commun (Camb). 2005 Mar 21(11):1384-6. doi: 10.1039/b415847d. Epub 2005 Jan 17.
DOI:10.1039/b415847d
PMID:15756311
Abstract
Enzymatic modifications of split and mix libraries were followed by "pulling down" onto a 2-dimensional DNA microarray, via PNA tagging; this allowed complete library interrogation of all members of the split and mix library.
摘要
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