Amberger C C, Dittmann H, Overkamp D, Brechtel K, Bares R, Kötter I
Medizinische Klinik und Polikliniken der Eberhardt-Karls-Universität Tübingen, Abteilung II Hämatologie, Onkologie, Immunologie und Rheumatologie, Otfried-Müller-Strasse 10, 72076 Tübingen, Germany.
Z Rheumatol. 2005 Feb;64(1):32-9. doi: 10.1007/s00393-005-0639-2.
Diagnosis and treatment of FUO or systemic inflammation with unknown reason are still a great challenge for the treating physician. We used (18)F-FDG-PET for further diagnostic work in patients in whom a diagnosis could not be established despite intensive diagnostic efforts.
METHODS/RESULTS: We studied nine patients with (18)F-FDG-PET. Two female patients with known Takayasu's arteritis but undefined disease activity, and seven patients with the clinical suspicion of an underlying large vessel vasculitis. The diagnosis of active vasculitis could be confirmed by the PET-results in eight patients. Active vasculitis could be nearly ruled out in one. The diagnoses could be confirmed by follow-up visits.
(18)F-FDG-PET is a useful diagnostic tool in patients with unclear systemic inflammation and FUO. Especially when large vessel vasculitis is suspected, further diagnostic work by PET seems to be of benefit. Furthermore, it offers the opportunity to evaluate disease activity and to check which vessels are involved.
不明原因发热（FUO）或全身性炎症的诊断和治疗对治疗医生来说仍然是一个巨大的挑战。对于那些尽管进行了深入的诊断努力仍无法确诊的患者，我们使用（18）F-FDG-PET进行进一步的诊断工作。
方法/结果：我们研究了9例接受（18）F-FDG-PET检查的患者。其中2例已知患有大动脉炎但疾病活动度不明确的女性患者，以及7例临床怀疑患有潜在大血管血管炎的患者。PET结果证实8例患者存在活动性血管炎。几乎排除了1例患者存在活动性血管炎。诊断结果通过随访得以证实。
（18）F-FDG-PET是诊断不明原因全身性炎症和FUO患者的有用诊断工具。特别是当怀疑存在大血管血管炎时，PET进一步的诊断工作似乎有益。此外，它还提供了评估疾病活动度以及检查哪些血管受累的机会。
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