Cisneros-Herreros José Miguel, Sánchez-González Manuela, Prados-Blanco M Trinidad, Llanos-Rodríguez Cristina, Vigil-Martín Eduardo, Soto-Espinosa de los Monteros Basilio, Pachón-Díaza Jerónimo
Servicio de Enfermedades Infecciosas, Hospitales Universitarios Virgen del Rocío, Sevilla, Spain.
Enferm Infecc Microbiol Clin. 2005 Mar;23(3):135-9. doi: 10.1157/13072162.
Culture of emergency room blood samples is common practice, but open to controversy. As compared to other emergency tests, blood collection requires twice as much time and needs a refined technique to avoid contamination, and the study has no immediate diagnostic utility.
This prospective study includes consecutive adult patients with positive emergency room blood cultures. We analyzed the diagnostic sensitivity and contamination rate of the cultures and the etiology, clinical features and prognosis of the bacteremias encountered.
During the study period, 5.2 blood cultures were indicated per 1000 patients attended in the emergency room. The diagnostic yield (positive blood cultures/total cultures) was 20% and the contamination rate (contaminated blood cultures/total cultures) was 1%. The incidence of bacteriemia was 0.99 episodes per 1000 patients attended in the emergency room and 10.3 episode per 1000 hospitalized patients. Gram-negative bacteria predominated (57%). Sepsis was the most frequent clinical manifestation (50%), followed by severe sepsis (40%) and septic shock (10%). Mortality was 22%. Diabetes mellitus and severe sepsis/septic shock were independent factors associated with mortality.
Diagnostic performance and quality of emergency room blood cultures was high. The predominant etiology was gram-negative bacteria. Patients had a severe clinical presentation. Diabetes mellitus and severe sepsis and/or septic shock were independent prognostic factors of mortality.
急诊室血样培养是常见做法,但存在争议。与其他急诊检查相比,采血需要两倍的时间,且需要精湛的技术以避免污染,并且该检查没有即时诊断效用。
这项前瞻性研究纳入了急诊室血培养呈阳性的连续成年患者。我们分析了培养的诊断敏感性和污染率以及所遇到的菌血症的病因、临床特征和预后。
在研究期间,每1000名在急诊室就诊的患者中有5.2次血培养检查。诊断阳性率(阳性血培养数/总培养数)为20%,污染率(污染血培养数/总培养数)为1%。菌血症的发生率为每1000名在急诊室就诊的患者中0.99例,每1000名住院患者中10.3例。革兰氏阴性菌占主导(57%)。脓毒症是最常见的临床表现(50%),其次是严重脓毒症(40%)和脓毒性休克(10%)。死亡率为22%。糖尿病以及严重脓毒症/脓毒性休克是与死亡率相关的独立因素。
急诊室血培养的诊断性能和质量较高。主要病因是革兰氏阴性菌。患者临床表现严重。糖尿病以及严重脓毒症和/或脓毒性休克是死亡率的独立预后因素。