桥本甲状腺炎的免疫遗传学
Immunogenetics of Hashimoto's thyroiditis.
作者信息
Chistiakov Dimitry A
机构信息
Laboratory of Aquatic Ecology, Katholieke Universiteit Leuven, Ch, De Beriotstraat 32, B-3000 Leuven, Belgium.
出版信息
J Autoimmune Dis. 2005 Mar 11;2(1):1. doi: 10.1186/1740-2557-2-1.
Abstract
Hashimoto's thyroiditis (HT) is an organ-specific T-cell mediated disease. It is a complex disease, with a strong genetic component. To date, significant progress has been made towards the identification and functional characterization of HT susceptibility genes. In this review, we will summarize the recent advances in our understanding of the genetic input to the pathogenesis of HT.
摘要
桥本甲状腺炎（HT）是一种器官特异性T细胞介导的疾病。它是一种复杂疾病，具有很强的遗传成分。迄今为止，在HT易感基因的鉴定和功能表征方面已取得显著进展。在本综述中，我们将总结目前在理解HT发病机制的遗传因素方面取得的最新进展。
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