Silvestri Amy J
Department of Psychology, Indiana University Purdue University Fort Wayne, Fort Wayne, IN 46805, USA.
Physiol Behav. 2005 Mar 16;84(3):343-9. doi: 10.1016/j.physbeh.2004.11.011.
Previous research has demonstrated that rapid eye movement (REM), or paradoxical, sleep deprivation can interfere with the retention of certain types of learning tasks, particularly spatial learning. The present study investigated the effects of 6 h of REM sleep deprivation on the retention and extinction of both cued and contextual conditioning tasks in rats. Sleep-deprived animals showed normal retention of both types of conditioning tasks but retarded extinction of the cued task and a trend toward attenuated spontaneous recovery of the contextual task. The results provide further evidence for the involvement of REM sleep in learning and memory processes.
先前的研究表明，快速眼动（REM）睡眠或异相睡眠剥夺会干扰某些类型学习任务的记忆保持，尤其是空间学习。本研究调查了6小时REM睡眠剥夺对大鼠线索性条件反射任务和情境性条件反射任务的记忆保持及消退的影响。睡眠剥夺的动物在两种类型的条件反射任务中均表现出正常的记忆保持，但线索性任务的消退延迟，情境性任务的自发恢复有减弱趋势。这些结果为REM睡眠参与学习和记忆过程提供了进一步的证据。
