Suppr超能文献

吉米沙星的重现性以及使用赛默飞世尔商业干板比较氟喹诺酮类药物的最低抑菌浓度结果

Reproducibility of gemifloxacin and comparison fluoroquinolone MIC results using Sensititre commercial dry-form panels.

作者信息

Ross James E, Sader Helio S, Fritsche Thomas R, Jones Ronald N

机构信息

The JONES Group/JMI Laboratories, North Liberty, IA 52317, USA.

出版信息

Diagn Microbiol Infect Dis. 2005 Mar;51(3):219-21. doi: 10.1016/j.diagmicrobio.2004.11.005.

Abstract

This study examined the ability of commercial dry-form broth microdilution panels (Sensititre, TREK Diagnostics, Cleveland, OH) to produce accurate minimum inhibitory concentration (MIC) results for gemifloxacin, a new fluoroquinolone. Reproducibility for gemifloxacin was 100.0% for on-scale values within +/-1 log2 dilution for same- and between-day comparisons. Newer comparator fluoroquinolones (sparfloxacin, sitafloxacin, and moxifloxacin) also showed excellent reproducibility (100.0%) for on-scale results analyzed at +/-1 log2 dilution for same- and between-day comparisons. Newer and investigational fluoroquinolone agents, including gemifloxacin, can be tested with confidence using these dry-form MIC panels.

摘要

本研究检测了商业化干式肉汤微量稀释板(Sensititre,TREK诊断公司,俄亥俄州克利夫兰)对新型氟喹诺酮类药物吉米沙星产生准确最低抑菌浓度(MIC)结果的能力。对于吉米沙星,在同一天及不同日期比较中对数2稀释度±1范围内的标度值,其重现性为100.0%。新型对照氟喹诺酮类药物(司帕沙星、西他沙星和莫西沙星)在同一天及不同日期比较中对数2稀释度±1分析标度结果时,也显示出优异的重现性(100.0%)。使用这些干式MIC板可以放心地检测包括吉米沙星在内的新型和研究性氟喹诺酮类药物。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验