全身应用抗生素未能预防一名支气管扩张症患者发生继发性内源性眼内炎。
Failure of systemic antibiotic in preventing sequential endogenous endophthalmitis of a bronchiectasis patient.
作者信息
Chan Wai-Man, Liu David T L, Fan Dorothy S P, Lau Teresa T Y, Lam Dennis S C
机构信息
Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, People's Republic of China.
出版信息
Am J Ophthalmol. 2005 Mar;139(3):549-50. doi: 10.1016/j.ajo.2004.08.058.
PURPOSE
To report a rare presentation of bilateral, sequential Pseudomonas aeruginosa endogenous endophthalmitis in a woman with bronchiectasis.
DESIGN
Interventional case report.
METHODS
A 69-year-old woman with bronchiectasis developed right and then left endogenous endophthalmitis with the microbial of P. aeruginosa, even though a course of 3-week intravenous ceftazidime antibiotic was prescribed.
RESULTS
The presentation of endogenous endophthalmitis in the right eye was late, and final visual acuity was hand movements. The condition was recognized much earlier in the left eye, and the infection was treated early on with vitrectomy and intravitreal antibiotics. Visual acuity at 1 year was stable at 20/40.
CONCLUSION
Systemic antibiotic failed to eradicate the primary source of Pseudomonas infection in the bronchiectasis patient. Unusual, painful red eye may be the presenting feature of endogenous endophthalmitis. Early vitrectomy may be considered in endogenous endophthalmitis caused by virulent pathogens such P. aeruginosa.
目的
报告一名患有支气管扩张症的女性罕见地出现双侧、相继发生的铜绿假单胞菌性内源性眼内炎。
设计
介入性病例报告。
方法
一名69岁患有支气管扩张症的女性先后出现右眼和左眼的内源性眼内炎，病原体为铜绿假单胞菌，尽管已给予为期3周的静脉注射头孢他啶抗生素治疗。
结果
右眼内源性眼内炎的表现出现较晚，最终视力为手动。左眼的病情更早被发现，感染早期即接受了玻璃体切割术和玻璃体内注射抗生素治疗。1年后视力稳定在20/40。
结论
全身性抗生素未能根除支气管扩张症患者铜绿假单胞菌感染的主要来源。不寻常的、疼痛的红眼可能是内源性眼内炎的表现特征。对于由铜绿假单胞菌等毒性病原体引起的内源性眼内炎，可考虑早期进行玻璃体切割术。
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