一种新的磷酸吡哆醛生物合成途径的重构与生化特性分析
Reconstitution and biochemical characterization of a new pyridoxal-5'-phosphate biosynthetic pathway.
作者信息
Burns Kristin E, Xiang Yun, Kinsland Cynthia L, McLafferty Fred W, Begley Tadhg P
机构信息
Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, USA.
出版信息
J Am Chem Soc. 2005 Mar 23;127(11):3682-3. doi: 10.1021/ja042792t.
PMID:15771487
Abstract
The substrates for Bacillus subtilis PLP synthase (YaaD and YaaE) are identified, and the first reconstitution of PLP biosynthesis using this pathway is described. Three partial reactions catalyzed by YaaD are also identified.
摘要
确定了枯草芽孢杆菌磷酸吡哆醛合酶（YaaD和YaaE）的底物，并描述了首次使用该途径重建磷酸吡哆醛生物合成的过程。还确定了由YaaD催化的三个部分反应。
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