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[Expression of glucose transporter 1 in the blood-brain barrier around hematoma in rats with cerebral hemorrhage].

作者信息

Li Zhong-Qiu, Lu Bing-Xun, Lü Tian-Ming

机构信息

Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.

出版信息

Di Yi Jun Yi Da Xue Xue Bao. 2005 Mar;25(3):339-41.

Abstract

OBJECTIVE

To observe the expression of glucose transporter 1 (GLUT1) in the blood-brain barrier around the hematoma in rats with cerebral hemorrhage.

METHOD

Brain tissue around the hematoma in rats with cerebral hemorrhage was prepared for GLUT1 detection by immunohistochemistry.

RESULT

The expression of GLUT1 upregulated within 48 h after cerebral hemorrhage and downregulated afterwards.

CONCLUSION

Protective reaction of the blood-brain barrier can be initiated to ensure glucose supply to the neurons against the injury by cerebral hemorrhage.

摘要

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