利福平加吡嗪酰胺诱发肝炎，一名30岁潜伏性结核男性因此需住院治疗。
Rifampin plus pyrazinamide-induced hepatitis requiring hospitalization in a 30-y-old male with latent tuberculosis.
作者信息
Potolidis Evangelos, Mantadakis Elpis, Zeniodi Maria-Helen, Samonis George
机构信息
Department of Internal Medicine, University Hospital of Heraklion, Heraklion, Greece.
出版信息
Scand J Infect Dis. 2005;37(2):155-7.
PMID:15773037
Abstract
The case of a 30-y-old male with latent tuberculosis who developed chemical hepatitis requiring hospitalization after 50 d of treatment with rifampin and pyrazinamide is reported. This case justifies the CDC guidelines that were updated on 31 August 2003 advising against the use of this brief regimen for patients with latent tuberculosis due to its risk for hepatotoxicity.
摘要
报告了一名30岁男性潜伏性结核患者的病例，该患者在接受利福平及吡嗪酰胺治疗50天后发生药物性肝炎，需住院治疗。该病例证明了美国疾病控制与预防中心（CDC）于2003年8月31日更新的指南是合理的，该指南建议，由于存在肝毒性风险，不应对潜伏性结核患者使用这种短程治疗方案。
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