Dvorkin Lee S, Knowles Charles H, Scott S Mark, Williams Norman S, Lunniss Peter J
Academic Department of Surgery (GI Physiology Unit), Royal London Hospital, Whitechapel, London, United Kingdom.
Dis Colon Rectum. 2005 Apr;48(4):824-31. doi: 10.1007/s10350-004-0834-2.
Rectal intussusception is a common finding at evacuation proctography; however, its significance has been debated. This study was designed to characterize clinically and physiologically a large group of patients with rectal intussusception and test the hypothesis that certain symptoms are predictive of this finding on evacuation proctography.
A total of 896 patients underwent evacuation proctography from which three groups were identified: those with isolated rectal intussusception (n = 125), those with isolated rectocele (n = 100), and those with both abnormalities (n = 152). Multivariate analyses were used to identify symptoms predictive of findings by evacuation proctography.
The symptoms of anorectal pain and prolapse were highly predictive of the finding of isolated intussusception over rectocele (odds ratio, 3.6, P = 0.006; odds ratio, 4.9, P < 0.001) or combined intussusception and rectocele (odds ratio, 2.9, P = 0.02; odds ratio, 2.4, P = 0.03). The symptom of "toilet revisiting" was associated with the finding of rectoanal intussusception (odds ratio, 3.55, P = 0.04). Although patients with mechanically obstructing intussuscepta evacuated slower and less completely (P < 0.001) than those with nonobstructing intussuscepta, no symptom was predictive of this finding on evacuation proctography.
Although certain symptoms are predictive of the finding of rectal intussusception, there is a wide overlap with symptoms of rectocele, another common cause of evacuatory dysfunction. Furthermore, the observation that "obstruction to evacuation" made on proctography had no impact on the incidence of evacuatory symptoms suggests that beyond simply demonstrating the presence of an intussusception, analysis of proctography and subclassifying intussusception morphology seems of little clinical significance, and selection for surgical intervention on the basis of proctographic findings may be illogical.
直肠套叠是排粪造影时的常见表现;然而,其意义一直存在争议。本研究旨在从临床和生理方面对一大组直肠套叠患者进行特征描述,并检验某些症状可预测排粪造影这一发现的假设。
共有896例患者接受了排粪造影,从中确定了三组:单纯直肠套叠患者(n = 125)、单纯直肠膨出患者(n = 100)以及同时存在这两种异常的患者(n = 152)。采用多变量分析来确定可预测排粪造影结果的症状。
肛门直肠疼痛和脱垂症状高度提示单纯套叠而非直肠膨出(比值比,3.6,P = 0.006;比值比,4.9,P < 0.001),或提示合并套叠和直肠膨出(比值比,2.9,P = 0.02;比值比,2.4,P = 0.03)。“如厕后反复排便”症状与直肠肛管套叠的发现相关(比值比,3.55,P = 0.04)。尽管机械性梗阻性套叠患者的排空速度比非梗阻性套叠患者慢且不完全(P < 0.001),但没有症状可预测排粪造影的这一结果。
尽管某些症状可预测直肠套叠的发现,但与直肠膨出(排空功能障碍的另一个常见原因)的症状有很大重叠。此外,排粪造影显示的“排空梗阻”对排空症状发生率无影响这一观察结果表明,除了简单显示套叠的存在外,排粪造影分析和套叠形态亚分类似乎临床意义不大,基于排粪造影结果选择手术干预可能不合理。