过去二十年韩国糖尿病酮症酸中毒的临床特征
Clinical characteristics of diabetic ketoacidosis in Korea over the past two decades.
作者信息
Ko S-H, Lee W-Y, Lee J-H, Kwon H-S, Lee J-M, Kim S-R, Moon S-D, Song K-H, Han J-H, Ahn Y-B, Yoo S-J, Son H-Y
机构信息
Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.
出版信息
Diabet Med. 2005 Apr;22(4):466-9. doi: 10.1111/j.1464-5491.2005.01450.x.
AIMS
The aim of this study was to investigate changes in the clinical characteristics of diabetic ketoacidosis (DKA) in Korea over the last two decades.
METHODS
A retrospective medical record review of all episodes of DKA from 1982 to 2002 in four University-affiliated urban hospitals in Korea was performed. A total of 255 episodes of DKA (217 patients) were identified and divided into three consecutive 7-year periods to compare trends over time. Clinical characteristics including precipitating factors and hospital mortality were analyzed.
RESULTS
A dramatic increase in DKA admissions has occurred over the last two decades, accompanied by a marked increase in admissions of diabetic patients. The clinical characteristics of DKA remained constant over the observation period. Non-compliance to treatment was the most common precipitating factor of DKA. A total of 30 patients died in hospital (11.8% of all episodes). Older age and infection appeared to influence mortality.
CONCLUSIONS
Our results suggest that rapidly increasing episodes of DKA in Korea, in parallel with increases in the numbers of diabetic patients, continue to be associated with significant mortality.
目的
本研究旨在调查过去二十年间韩国糖尿病酮症酸中毒（DKA）临床特征的变化。
方法
对韩国四所大学附属医院1982年至2002年间所有DKA发作病例进行回顾性病历审查。共识别出255例DKA发作（217例患者），并将其分为连续三个7年时间段以比较随时间的趋势。分析了包括诱发因素和医院死亡率在内的临床特征。
结果
在过去二十年中，DKA入院人数急剧增加，同时糖尿病患者入院人数显著增加。在观察期内，DKA的临床特征保持不变。治疗依从性差是DKA最常见的诱发因素。共有30例患者在医院死亡（占所有发作病例的11.8%）。年龄较大和感染似乎影响死亡率。
结论
我们的结果表明，韩国DKA发作病例迅速增加，与糖尿病患者数量增加同时出现，仍然与显著的死亡率相关。
Zotero 插件