[小儿喉罩置入和气管插管时的呼气末七氟烷浓度]
[End-tidal sevoflurane concentrations for laryngeal mask airway insertion and tracheal intubation in children].
作者信息
Grabowska-Gaweł Anna
机构信息
Zakład Pielegniarstwa w Intensywnej Opiece Medycznej Akademii Medycznej, Bydgoszczy.
出版信息
Przegl Lek. 2004;61(7):783-5.
BACKGROUND
Sevoflurane, a new inhalation anesthetic agent characterized by a low blood-gas partition coefficient and nonpungent odor, appears suitable as an induction agent for children. This study was conducted to determine the sevoflurane concentration required for tracheal intubation and insertion laryngeal mask in children.
METHODS
Thirty patients, aged 3-7 years, scheduled for surgery during general anesthesia were randomly assigned into two groups: Group I (n=15)--tracheal intubation (IT), Group II (n=15)--laryngeal mask insertion (LMI). After the predetermined end-tidal concentration of the sevoflurane, tracheal intubation or laryngeal mask insertion was attempted without neuromuscular relaxants.
RESULTS
Sevoflurane MAC-LMI was 1.53 +/- 0.23%, sevoflurane MAC-TI was 2.35 +/- 0.31%, significantly greater than MAC-LMI.
CONCLUSIONS
Laryngeal mask insertion can be performed at a lesser sevoflurane concentration than that required for tracheal intubation.
背景
七氟烷是一种新型吸入麻醉剂，具有低血气分配系数和无刺激性气味的特点，似乎适合作为儿童的诱导麻醉剂。本研究旨在确定儿童气管插管和插入喉罩所需的七氟烷浓度。
方法
30例年龄在3至7岁、计划在全身麻醉下进行手术的患者被随机分为两组：第一组（n = 15）——气管插管（IT）组，第二组（n = 15）——喉罩插入（LMI）组。在达到预定的七氟烷呼气末浓度后，在不使用神经肌肉松弛剂的情况下尝试进行气管插管或喉罩插入。
结果
七氟烷喉罩插入的最低肺泡有效浓度（MAC-LMI）为1.53±0.23%，七氟烷气管插管的最低肺泡有效浓度（MAC-TI）为2.35±0.31%，显著高于MAC-LMI。
结论
插入喉罩时所需的七氟烷浓度低于气管插管所需的浓度。
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