伴有横纹肌肉瘤成分的骨肉瘤，即所谓的骨恶性间叶瘤。
Osteosarcoma with rhabdomyosarcomatous component or so-called malignant mesenchymoma of bone.
作者信息
Mrad K, Sassi S, Smida M, Oubiche F, Mekni A, Romdhane K Ben
机构信息
Surgical Pathology Department, Salah Azaiez Institute, 1006 Bab Saadoun, Tunis, Tunisia.
出版信息
Pathologica. 2004 Dec;96(6):475-8.
BACKGROUND
Primary malignant mesenchymoma of the bone is a rare neoplasm consisting of two or more unrelated malignant mesenchymal components. The literature reports fewer than 20 cases, most of which were composed of osteosarcoma and liposarcoma.
OBSERVATION
We report an exceedingly rare case of primary malignant mesenchymoma of bone composed of rhabdomyosarcoma, osteosarcoma, and a minor chondrosarcoma component, arising in the right proximal humerus of a 15-year-old girl. The rhabdomyosarcomatous component was present in the initial biopsy and persisted in surgical specimen following chemotherapy.
CONCLUSION
Effect of chemotherapy is enigmatic since rhabdomyosarcomatous component could appear, persist or disappear after chemotherapy according to literature.
背景
原发性骨恶性间叶瘤是一种罕见的肿瘤，由两种或更多不相关的恶性间叶成分组成。文献报道的病例少于20例，其中大多数由骨肉瘤和脂肪肉瘤组成。
观察
我们报告了一例极为罕见的原发性骨恶性间叶瘤，由横纹肌肉瘤、骨肉瘤和少量软骨肉瘤成分组成，发生于一名15岁女孩的右肱骨近端。横纹肌肉瘤成分在初始活检中就已存在，化疗后在手术标本中依然存在。
结论
化疗的效果难以捉摸，因为根据文献，横纹肌肉瘤成分在化疗后可能出现、持续存在或消失。
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