Isaacson Brandon, Kileny Paul R, El-Kashlan Hussam K
University of Michigan Hospitals, Department of Otolaryngology-Head and Neck Surgery, Ann Arbor, Michigan, USA.
Otol Neurotol. 2005 Mar;26(2):270-3. doi: 10.1097/00129492-200503000-00025.
Evaluate the utility of a statistical equation using two independent intraoperative monitoring parameters in predicting long-term facial nerve function.
Retrospective case review.
Tertiary care hospital.
Sixty patients undergoing resection of vestibular schwannomas with intraoperative facial nerve monitoring at a single institution.
All patients underwent microsurgical resection of vestibular schwannomas with the use of intraoperative cranial nerve monitoring.
Final facial nerve outcome measured using the House-Brackmann scale at least 6 months after microsurgical resection.
Five out of 60 (8.3%) patients demonstrated significant long-term weakness (i.e., House-Brackmann grade III or worse). Intraoperative monitoring parameters (proximal stimulation threshold, proximal-to-distal response amplitude ratio) were accurate in predicting increased risk of long-term facial nerve dysfunction when used in a logistic regression model. A Student's t test confirmed the equation result was statistically significant in differentiating long-term facial nerve outcomes.
Patients with immediate weakness are at higher risk of having long-term poor facial nerve function. The use of intraoperative monitoring parameters was reliable in predicting facial nerve outcomes. Patients with permanent facial nerve dysfunction often require rehabilitative procedures. The ability to predict facial nerve outcomes with intraoperative monitoring may allow early rehabilitative procedures to improve quality of life and prevent ocular complications.
评估使用两个独立的术中监测参数的统计方程在预测长期面神经功能方面的效用。
回顾性病例分析。
三级医疗中心。
在单一机构接受前庭神经鞘瘤切除并术中进行面神经监测的60例患者。
所有患者均在术中颅神经监测下接受前庭神经鞘瘤显微切除术。
显微切除术后至少6个月使用House-Brackmann量表测量的最终面神经结果。
60例患者中有5例(8.3%)出现明显的长期无力(即House-Brackmann分级为III级或更差)。术中监测参数(近端刺激阈值、近端与远端反应幅度比)用于逻辑回归模型时,在预测长期面神经功能障碍风险增加方面是准确的。Student t检验证实该方程结果在区分长期面神经结果方面具有统计学意义。
即刻出现无力的患者长期面神经功能差的风险更高。术中监测参数在预测面神经结果方面是可靠的。永久性面神经功能障碍的患者通常需要康复治疗。术中监测预测面神经结果的能力可能有助于早期康复治疗,以改善生活质量并预防眼部并发症。