磁县食管癌高危人群的年龄范围。
Age scope of high-risk population for esophageal cancer in Ci county.
作者信息
Chen Zhi-Feng, Hou Jun, Ding Zhen-Wei, Guo Cui-Lan, Qiao Cui-Yun, Song Guo-Hui, Li Shao-Sen, Zhang Jian-Hui, He Yu-Tong
机构信息
Hebei Cancer Institute, Shijiazhuang 050011, Hebei Province, China.
出版信息
World J Gastroenterol. 2005 Mar 28;11(12):1818-21. doi: 10.3748/wjg.v11.i12.1818.
AIM
To define the age scope of high-risk population for esophageal cancer (EC) in Ci county.
METHODS
The results of endoscopic examination of 2 013 subjects, cytological screening of 16 763 persons and records of 9 265 patients with EC were analyzed by Ridit methods, the standard age group was 45-49 year group.
RESULTS
The average age of patients with moderate esophageal epithelium dysplasia by endoscopic examination was 53.5 years, of severe esophageal epithelium dysplasia, 51.4 years, early EC, 55.6 years. The average age of stage one severe epithelium dysplasia (SEEDI) by cytological screening was 51.2 years, of stage two severe epithelium esophageal dysplasia (SEED II) 51.6 years, of advanced EC 61.7 years. In the group of 40-year olds, the value of Ridit by pathological diagnosis was 0.46, 95% CI, 0.45-0.47, that by cytological diagnosis was 0.45, 95% CI, 0.43-0.47. As the age increased at five-year intervals, the value of Ridit increased significantly.
CONCLUSION
In Ci county of a high incidence area of EC, the age definition of high-risk population should be above 45 years.
目的
明确磁县食管癌高危人群的年龄范围。
方法
采用Ridit法分析2013例受检者的内镜检查结果、16763人的细胞学筛查结果及9265例食管癌患者的病历资料，标准年龄组为45 - 49岁组。
结果
内镜检查中食管上皮中度不典型增生患者的平均年龄为53.5岁，重度不典型增生患者为51.4岁，早期食管癌患者为55.6岁。细胞学筛查中一期重度上皮不典型增生（SEEDI）患者的平均年龄为51.2岁，二期重度食管上皮不典型增生（SEED II）患者为51.6岁，晚期食管癌患者为61.7岁。在40岁组中，病理诊断的Ridit值为0.46，95%可信区间为0.45 - 0.47，细胞学诊断的Ridit值为0.45，95%可信区间为0.43 - 0.47。以5年为间隔随着年龄增加，Ridit值显著升高。
结论
在食管癌高发区磁县，高危人群的年龄界定应为45岁以上。
Zotero 插件