Fumeaux Z, Stoermann Chopard C
Service de Néphrologie Département de Médecine Interne, Hôpitaux Universitaires de Genève.
Rev Med Suisse. 2005 Feb 23;1(8):557-8, 560-1.
In clinical situations of electrolytic or acid-base disorders, the measure of electrolytes concentration and osmolality in a urine sample, which is called the urinary spot, is a simple way to guide the diagnosis and therapy. The interpretation of results must take into account the patient's history and clinical examination. The urine sodium concentration and urine osmolality are key elements in the diagnosis of dysnatremias and in renal failure. The urine chloride concentration is useful in the diagnosis of acid-base disorders. The potassium excretion in the urine, which is regulated mainly by aldosterone, is particularly helpful in the case of hypokaliemia. Finally, the determination of the transtubular potassium gradient is a valuable tool for the diagnosis of hypoaldosteronism.
在电解质或酸碱紊乱的临床情况下,测量尿液样本中的电解质浓度和渗透压(即所谓的随机尿)是指导诊断和治疗的一种简单方法。结果的解读必须考虑患者的病史和临床检查。尿钠浓度和尿渗透压是诊断钠代谢紊乱和肾衰竭的关键要素。尿氯浓度对酸碱紊乱的诊断有用。尿钾排泄主要受醛固酮调节,在低钾血症情况下特别有帮助。最后,跨肾小管钾梯度的测定是诊断醛固酮缺乏症的一项有价值的工具。