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膝关节软骨缺损的多骨软骨关节镜移植术(镶嵌成形术):2年随访的前瞻性研究结果

Multiple osteochondral arthroscopic grafting (mosaicplasty) for cartilage defects of the knee: prospective study results at 2-year follow-up.

作者信息

Marcacci Maurilio, Kon Elizaveta, Zaffagnini Stefano, Iacono Francesco, Neri Maria Pia, Vascellari Alberto, Visani Andrea, Russo Alessandro

机构信息

Istituti Ortopedici Rizzoli, Bologna, Italy.

出版信息

Arthroscopy. 2005 Apr;21(4):462-70. doi: 10.1016/j.arthro.2004.12.003.

Abstract

PURPOSE

To prospectively evaluate the mosaicplasty technique for treatment of femoral condyle cartilage lesions (Outerbridge grade IV) less than 2.5 cm2 in homogeneous group of young active patients.

TYPE OF STUDY

Case series.

METHODS

Thirty-seven patients (10 female, 27 male; mean age, 29.5 years) with full-thickness knee chondral lesions were treated by the arthroscopic mosaicplasty technique. All patients practiced sports. There were 12 ACL reconstructions, 11 medial meniscectomies, and 8 lateral meniscectomies associated; 10 meniscectomies, 9 ACL reconstructions, and 5 cartilage reparative operations had been previously performed. All patients were evaluated at a 2-year follow-up. The International Cartilage Repair Society (ICRS) form, return to sports, computed tomography, or magnetic resonance imaging were used for clinical evaluation. In some cases, second-look arthroscopy was performed.

RESULTS

The ICRS showed 78.3% good and excellent results; 27 patients returned to sports at the same level and 5 at a lower level, but 5 were not able to resume sports. Results in the lateral condyles were significantly better than those in medial condyles, and younger patients had a better clinical outcome than did older patients. Cases with associated surgery had better clinical results; previous surgery did not significantly influence the clinical outcome.

CONCLUSIONS

The results of this technique at medium-term follow-up are encouraging with 78.3% clinically satisfactory results. Better results can be obtained in young patients with associated surgery, with localized grade 4 lesions of the lateral condyles. This arthroscopic 1-step surgery appears to be a valid solution for the treatment of grade III-IV cartilage defects not more than 2.5 cm2.

LEVEL OF EVIDENCE

Level IV, Case Series.

摘要

目的

前瞻性评估马赛克成形术治疗年轻活跃患者中面积小于2.5平方厘米的股骨髁软骨损伤(Outerbridge Ⅳ级)的技术效果。

研究类型

病例系列研究。

方法

采用关节镜下马赛克成形术治疗37例全层膝关节软骨损伤患者(10例女性,27例男性;平均年龄29.5岁)。所有患者均进行体育活动。同时进行了12例前交叉韧带重建、11例内侧半月板切除术和8例外侧半月板切除术;此前还进行过10例半月板切除术、9例前交叉韧带重建和5例软骨修复手术。所有患者均在2年随访时进行评估。使用国际软骨修复协会(ICRS)表格、恢复运动情况、计算机断层扫描或磁共振成像进行临床评估。部分病例进行了二次关节镜检查。

结果

ICRS显示优良率为78.3%;27例患者恢复到相同运动水平,5例恢复到较低运动水平,但5例无法恢复运动。外侧髁的结果明显优于内侧髁,年轻患者的临床结局优于老年患者。合并手术的病例临床结果更好;既往手术对临床结局无显著影响。

结论

该技术中期随访结果令人鼓舞,临床满意率达78.3%。对于合并手术的年轻患者,外侧髁局限性4级损伤可获得更好的结果。这种关节镜下的一步手术似乎是治疗面积不超过2.5平方厘米的Ⅲ - Ⅳ级软骨缺损的有效方法。

证据水平

Ⅳ级,病例系列研究。

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