Porzezińska Maria, Słomiński Jan Marek
Akademia Medyczna w Gdańsku.
Przegl Lek. 2004;61(9):972-7.
Sarcoidosis is a multisystem disorder of unknown aetiology. Pathologically it is characterized by the presence of non-caseating epithelioid-cell granulomas in the lungs, intrathoracic lymph nodes and other affected organs. The clinical course of sarcoidosis is widely variable, ranging from asymptomatic but abnormal findings in chest radiography to progressive multiorgan disease, which leads to fibrosis with organ failure and functional impairment. The aim of this article is to familiarize physicians with clinical features and treatment of this disease.
结节病是一种病因不明的多系统疾病。病理上,其特征是在肺部、胸内淋巴结和其他受累器官中存在非干酪样上皮样细胞肉芽肿。结节病的临床病程差异很大,从胸部X线检查无明显症状但有异常发现到进行性多器官疾病,后者会导致器官衰竭和功能损害的纤维化。本文旨在让医生熟悉这种疾病的临床特征和治疗方法。