解旋酶基因在淋病奈瑟菌同源重组中的作用。
Role of the Rep helicase gene in homologous recombination in Neisseria gonorrhoeae.
作者信息
Kline Kimberly A, Seifert H Steven
机构信息
Department of Microbiology and Immunology, Northwestern University Feinberg University School of Medicine, 303 East Chicago Ave., Chicago, IL 60611, USA.
出版信息
J Bacteriol. 2005 Apr;187(8):2903-7. doi: 10.1128/JB.187.8.2903-2907.2005.
Abstract
In Escherichia coli, the Rep helicase has been implicated in replication fork progression, replication restart, homologous recombination, and DNA repair. We show that a Neisseria gonorrhoeae rep mutant is deficient in the homologous-recombination-mediated processes of DNA transformation and pilus-based colony variation but not in DNA repair.
摘要
在大肠杆菌中，Rep解旋酶与复制叉推进、复制重启、同源重组及DNA修复有关。我们发现，淋病奈瑟菌rep突变体在同源重组介导的DNA转化和菌毛介导的菌落变异过程中存在缺陷，但在DNA修复方面没有缺陷。
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