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与前列腺切除术后放疗相关的社会人口学因素。

Sociodemographic factors associated with postprostatectomy radiotherapy.

作者信息

Krupski T L, Kwan L, Litwin M S

机构信息

Department of Urology, David Geffen School of Medicine, School of Public Health, Jonsson Comprehensive Cancer Center, University of California, Los Angeles, California 90095-1738, USA.

出版信息

Prostate Cancer Prostatic Dis. 2005;8(2):184-8. doi: 10.1038/sj.pcan.4500791.

Abstract

PURPOSE

To determine if nonclinical factors affect the use of adjuvant radiation therapy after surgical resection of the prostate gland.

METHODS

Using the National Cancer Institute's Surveillance Epidemiology and End Results (SEER) public use data files, we identified men with localized/regional prostate cancer who underwent postprostatectomy radiotherapy within 4 months of surgery. We used 2000 Census information to ascribe a median education and income level to these men based on the county of residence and ethnicity.

RESULTS

Of 34,763 men who underwent surgical resection, 1549 received postprostatectomy radiotherapy. Those with higher tumor grade and from certain geographic regions (Seattle and Hawaii) had significantly higher rates of radiotherapy while being older and from other geographic regions (Detroit, Utah, and New Mexico) was protective. The use of additional radiation therapy was not affected by ethnicity, income level, or educational attainment.

CONCLUSIONS

We found no socioeconomic or demographic disparities in the receipt of postprostatectomy radiotherapy. Geographic variation in postprostatectomy radiotherapy may be explained by limited evidence supporting its use in clinical practice.

摘要

目的

确定非临床因素是否会影响前列腺手术切除后辅助放疗的使用。

方法

利用美国国立癌症研究所的监测、流行病学和最终结果(SEER)公共使用数据文件,我们识别出在手术后4个月内接受前列腺切除术后放疗的局限性/区域性前列腺癌男性患者。我们使用2000年人口普查信息,根据居住县和种族为这些男性确定教育程度和收入水平的中位数。

结果

在34763例接受手术切除的男性中,1549例接受了前列腺切除术后放疗。肿瘤分级较高以及来自某些地理区域(西雅图和夏威夷)的患者放疗率显著更高,而年龄较大以及来自其他地理区域(底特律、犹他州和新墨西哥州)则具有保护作用。额外放疗的使用不受种族、收入水平或教育程度的影响。

结论

我们发现在接受前列腺切除术后放疗方面不存在社会经济或人口统计学差异。前列腺切除术后放疗的地理差异可能是由于临床实践中支持其使用的证据有限所致。

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