Esfandiari Navid, Gotlieb Lynda, Casper Robert F
Toronto Centre for Advanced Reproductive Technology, Toronto, Ontario, Canada.
Fertil Steril. 2005 Apr;83(4):1041. doi: 10.1016/j.fertnstert.2004.10.034.
To report a case of successful triplet pregnancy in an acromegaly patient with IVF and embryo transfer.
Case report.
Tertiary center for assisted reproductive technologies.
PATIENT(S): A 33-year-old woman with acromegaly and primary infertility.
INTERVENTION(S): Controlled ovulation hyperstimulation and IVF/embryo-transfer treatment using gonadotropins.
MAIN OUTCOME MEASURE(S): Uncomplicated pregnancy course and successful take-home triplet infant girls.
RESULT(S): Successful ovarian stimulation and IVF is possible in acromegalic patients.
CONCLUSION(S): There may be an effect of elevated growth hormone resulting in increased ovarian response to gonadotropin, inducing hyperstimulation and high-order multiple pregnancies in these patients.
报告一例肢端肥大症患者通过体外受精和胚胎移植成功实现三胎妊娠的病例。
病例报告。
辅助生殖技术三级中心。
一名33岁患有肢端肥大症和原发性不孕症的女性。
使用促性腺激素进行控制性促排卵超刺激及体外受精/胚胎移植治疗。
孕期无并发症且成功抱回三胞胎女婴。
肢端肥大症患者可成功进行卵巢刺激和体外受精。
生长激素升高可能产生影响,导致这些患者的卵巢对促性腺激素反应增强,引发过度刺激和多胎妊娠。