Porto L, Kieslich M, Yan B, Schwabe D, Zanella F E, Lanfermann H
Neuroradiology Department, Institut für Neuroradiologie, Klinikum der Johann-Wolfgang-Goethe-Universität, Frankfurt am Main, Germany.
Neuropediatrics. 2005 Apr;36(2):112-6. doi: 10.1055/s-2005-837659.
We report three patients with primary extracerebral neuroblastoma and central nervous system (CNS) relapse. As the survival of children with metastatic neuroblastoma improves with recent advances in treatment, CNS involvement becomes more frequently detected. MR imaging of the brain and spine are strongly indicated in the follow-up of patients with increased risk of developing CNS disease.
我们报告了3例原发性脑外神经母细胞瘤并中枢神经系统(CNS)复发的患者。随着近年来治疗进展使转移性神经母细胞瘤患儿的生存率提高,CNS受累越来越频繁地被检测到。对于发生CNS疾病风险增加的患者,在随访中强烈建议进行脑部和脊柱的磁共振成像(MR)检查。