Janssens Jean-Paul, Laszlo André, Uldry Christophe, Titelion Véronique, Picaud Claudette, Michel Jean-Pierre
Geriatric University Hospital, Thônex, Switzerland.
Gerontology. 2005 May-Jun;51(3):174-8. doi: 10.1159/000083990.
Transcutaneous measurements of arterial blood gases (ABG) may decrease the need for repeated arterial puncture in older patients treated for acute cardiac or pulmonary disorders. However, age-related changes in skin perfusion, metabolism, or thickness may alter the validity of the technique.
To analyse the agreement between transcutaneous and arterial measurement of PaO2 and PaCO2 in older adults.
Prospective descriptive study performed in the intermediate-care unit of a geriatric university hospital and a pulmonary rehabilitation centre.
40 patients, aged 82.5+/-8 years (66-97), hemodynamically stable, without vasopressor treatment, underwent simultaneous measurement of arterial blood gases (ABG) and transcutaneous CO2 (TcPCO2) and O2 (TcPO2) with a Radiometer TINA TCM3 capnograph, and a probe T degrees set at 43 degrees C.
Correlation between PaCO2 and TcPCO2 was high (r2=0.86) with a low bias (-0.1 mm Hg) and limits of agreement quite compatible with clinical use: (8.3; -8.5 mm Hg). The probe was well tolerated without any cutaneous lesion even after prolonged recordings (up to 8 h). Conversely, although TcPO2 and PaO2 were significantly correlated, the variability around the regression line precludes the use of transcutaneous measurements for monitoring PaO2)in a clinical setting.
In older subjects, TcPCO2 (but not TcPO2) measurements are reliable when repeated assessment of ABG is warranted.
经皮测量动脉血气(ABG)可能会减少老年急性心脏或肺部疾病患者重复进行动脉穿刺的需求。然而,皮肤灌注、代谢或厚度的年龄相关变化可能会改变该技术的有效性。
分析老年人经皮和动脉测量PaO₂和PaCO₂之间的一致性。
在一所老年大学医院的中级护理单元和一个肺康复中心进行的前瞻性描述性研究。
40名年龄为82.5±8岁(66 - 97岁)、血流动力学稳定且未接受血管升压药治疗的患者,使用Radiometer TINA TCM3二氧化碳分析仪和设置为43℃的T型探头,同时测量动脉血气(ABG)、经皮二氧化碳(TcPCO₂)和经皮氧(TcPO₂)。
PaCO₂与TcPCO₂之间的相关性较高(r² = 0.86),偏差较低(-0.1 mmHg),一致性界限与临床应用相当兼容:(8.3;-8.5 mmHg)。即使长时间记录(长达8小时)后,探头耐受性良好,未出现任何皮肤损伤。相反,尽管TcPO₂与PaO₂显著相关,但回归线周围的变异性使得在临床环境中无法使用经皮测量来监测PaO₂。
在老年受试者中,当需要重复评估ABG时,TcPCO₂(而非TcPO₂)测量是可靠的。