Koerbel Andrei, Gharabaghi Alireza, Safavi-Abbasi Sam, Tatagiba Marcos, Samii Madjid
Department of Neurosurgery, International Neuroscience Institute, Hannover, Germany.
Neurosurg Focus. 2005 Apr 15;18(4):e10. doi: 10.3171/foc.2005.18.4.11.
The extraordinary improvement of patient outcome after surgical treatment for vestibular schwannomas is relatively recent and has occurred mainly over the last 30 years. The introduction of microsurgical techniques has resulted in increasing degrees of precise anatomical and functional preservation of the facial and cochlear nerves. An expanded microsurgical technique accompanied by continuous electrophysiological monitoring has resulted in marked changes in the primary goals for this surgery. Whereas in the past the primary goal of vestibular schwannoma management was to preserve the patient's life, the objective in vestibular schwannoma treatment today is to preserve neurological function. Long-term follow-up examinations show negligible recurrence rates, indicating that the aim of preservation of nerve function does not limit the completeness of tumor removal with modern neurosurgical techniques. Despite these advances in preserving the anatomical integrity of, for example, the cochlear nerve, losses of function and even deafness may occur postoperatively in some cases. Current biological and technical research in experimental and clinical settings addresses these problems. In this article, the authors report in detail the developments achieved in vestibular schwannoma surgery and the great clinicians to whom these results can be credited.
前庭神经鞘瘤手术治疗后患者预后的显著改善是相对较新的现象,主要发生在过去30年。显微外科技术的引入使得面神经和听神经在解剖和功能上的保留程度不断提高。扩展的显微外科技术结合持续的电生理监测,使得该手术的主要目标发生了显著变化。过去前庭神经鞘瘤治疗的主要目标是挽救患者生命,而如今前庭神经鞘瘤治疗的目标是保留神经功能。长期随访检查显示复发率极低,这表明在现代神经外科技术下,保留神经功能的目标并不限制肿瘤切除的彻底性。尽管在保留例如听神经的解剖完整性方面取得了这些进展,但在某些情况下,术后仍可能出现功能丧失甚至耳聋。目前在实验和临床环境中的生物学和技术研究正在解决这些问题。在本文中,作者详细报告了前庭神经鞘瘤手术取得的进展以及取得这些成果所归功的伟大临床医生。