米托蒽醌（诺维本）用于治疗多发性硬化症：新见解

Mitoxantrone (Novantrone) in multiple sclerosis: new insights.

作者信息

Neuhaus Oliver, Kieseier Bernd C, Hartung Hans-Peter

机构信息

Department of Neurology, Heinrich Heine University, Moorenstrasse 5, D 40225 Düsseldorf, Germany.

出版信息

Expert Rev Neurother. 2004 Jan;4(1):17-26. doi: 10.1586/14737175.4.1.17.

DOI:10.1586/14737175.4.1.17

Abstract

The conclusions of a recent study of mitoxantrone (Novantrone) in multiple sclerosis and the approval of several health authorities support its use in patients with active relapsing-remitting or secondary progressive multiple sclerosis. This drug profile provides an outline on relevant preclinical and clinical studies, discusses relevant side effects of the compound and places mitoxantrone in the context of other therapeutic approaches available against this disabling disorder.

摘要

最近一项关于米托蒽醌（诺万托龙）治疗多发性硬化症的研究结论以及多个卫生当局的批准，支持其用于活动性复发缓解型或继发进展型多发性硬化症患者。本药物简介概述了相关的临床前和临床研究，讨论了该化合物的相关副作用，并将米托蒽醌与针对这种致残性疾病的其他治疗方法进行了对比。

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