胞质分裂：肌球蛋白的新作用

Cytokinesis: new roles for myosin.

作者信息

Burgess David R

机构信息

Boston College, Biology Department , MA 02467, USA.

出版信息

Curr Biol. 2005 Apr 26;15(8):R310-1. doi: 10.1016/j.cub.2005.04.008.

DOI:10.1016/j.cub.2005.04.008

PMID:15854900

Abstract

Myosin II is the motor for cytokinesis, an event at the end of cell division during which the animal cell uses a contractile ring to pinch itself in half. New and surprising research shows that myosin, either through light chain phosphorylation or through its ATPase activity, also plays an important role in both the assembly and disassembly of the actin contractile ring.

摘要

肌球蛋白II是胞质分裂的动力蛋白，胞质分裂是细胞分裂末期的一个过程，在此过程中动物细胞利用收缩环将自身缢裂成两半。新的惊人研究表明，肌球蛋白无论是通过轻链磷酸化还是通过其ATP酶活性，在肌动蛋白收缩环的组装和拆卸过程中都发挥着重要作用。