Galogre A G, Maglakelidze N N, Tsagareli Z G
Natishvili Research Institute of Experimental Morphology, Tbilisi, Georgia.
Georgian Med News. 2005 Mar(120):71-4.
The aim of the work was to estimate morphological changes in cells of gingival mucous membrane in the experimental gingivitis model. Fifty rats with the body weight of 120-160 gr. were used in the experiment. Gingivitis was modeled by front teeth ligation after a preliminary exfoliation of mucous membrane in the dental neck area. The specimens were examined by histological method and electron microscopy on the 3rd, 5th, 14th and 28th days of the experiment. It has been shown that cellular population of plasmocytes, lymphocytes, fibroblasts and mast cells take part in the inflammatory process. In all the areas of microcirculation occurs transformation of endotheliocytes like papillas; the process of roughening of collagenous fibrils indicates their significant role in the inflammatory damage of gingiva.